Human Annexin A7 (ANXA7) Protein
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Description
Annexin A7 (ANXA7) protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A7 (ANXA7) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Gln466 |
| Origin | Human |
| Observed MW | 50.3 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 10 mM TrisHCl, 100 mM NaCl, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P20073-2 |
| Alias | ANXA7,ANX7,SNX |
| Background | Protein ANXA7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
ANXA7 is a calcium- and GTP-dependent membrane-binding protein that plays a key role in exocytosis, membrane repair, and cell signaling. It acts as a calcium sensor, facilitating the fusion of vesicles with the plasma membrane, particularly in processes such as neurotransmitter release and hormone secretion. ANXA7 is expressed in the brain, heart, and other tissues, where it contributes to cellular calcium homeostasis and cell survival mechanisms. Mutations or dysregulation of ANXA7 have been associated with neurodegenerative diseases, such as Parkinson's disease, and cancers, where it can act as a tumor suppressor by regulating cell proliferation and apoptosis. Its roles in membrane dynamics and calcium-dependent signaling underscore its importance in cellular communication and homeostasis.
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