Human Angiogenin (ANG) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ANG
proveedor
Abbexareference
abx166508Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Angiogenin Protein is a recombinant Human protein expressed in E. coli.
Background
Angiogenin (ANG) is a protein that plays a significant role in angiogenesis. It is a member of the ribonuclease superfamily, but unlike other members that primarily function in RNA degradation, angiogenin has distinct functions related to blood vessel formation and tissue repair. The primary role of angiogenin is to promote the growth of new blood vessels from existing ones. This is crucial in processes like wound healing, embryonic development, and tissue regeneration. Angiogenin has ribonuclease activity, meaning it can cleave RNA molecules. However, its angiogenic activity is independent of this enzymatic function. Angiogenin acts on endothelial cells, which line the inside of blood vessels. It stimulates these cells to proliferate, migrate, and form new blood vessels. It also promotes cell survival and protects cells from apoptosis (programmed cell death), which is important for the stability of newly formed blood vessels.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Angiogenin (ANG)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 18.0 kDa Observed MW (SDS-PAGE): 18 kDa Concentration: Prior to lyophilization: 400 µg/ml Sequence Fragment: Gln25-Pro147 Tag: N-terminal His tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ANG
dry ice
No
availability
Shipped within 5-7 working days.
alias
ANG,RNASE5,Ribonuclease 5
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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