Human Amyloid beta 40 (Abeta40) ELISA Kit

Este producto es parte de Abeta40 - Amyloid beta 40
Human Amyloid beta 40 (Abeta40) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

493.75€ (96 tests)

Elisa Kits Abeta40

proveedor

Abbexa

reference

abx053393

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Amyloid beta 40 (Abeta40) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Amyloid beta 40 (Abeta40) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.


Background

Abeta40 is a 40-amino acid peptide derived from the amyloid precursor protein (APP) through sequential cleavage by β-secretase and γ-secretase. It is the most abundant form of amyloid beta in the brain and cerebrospinal fluid, constituting the majority of amyloid beta peptides produced. Aβ40 plays a role in physiological processes, including neuronal activity modulation and synaptic plasticity. However, in pathological conditions like Alzheimer’s disease, Aβ40 aggregates to form amyloid plaques, a hallmark of the disease. Compared to Aβ42, Aβ40 is less prone to aggregation, but it is still involved in early-stage plaque formation. Elevated or imbalanced Aβ40 levels are associated with vascular amyloid deposition, contributing to cerebral amyloid angiopathy and cerebrovascular dysfunction, which exacerbate cognitive decline. Monitoring Aβ40 levels in cerebrospinal fluid is often used as a biomarker in Alzheimer’s research and diagnosis.

Características del producto

category

ELISA Kits


immunogen target

Amyloid beta 40 (Abeta40)


reactivity

Human


test range

15.6 pg/ml - 1000 pg/ml


sensitivity

9.38 pg/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

Aβ40|Amyloid Beta 40|Abeta 40|Beta-amyloid protein 40|Aβ|1-40


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

Abeta40


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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