Human AMP deaminase 1 (AMPD1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AMPD1
proveedor
Abbexareference
abx385732Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human AMP deaminase 1 (AMPD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adenosine Monophosphate Deaminase 1 (AMPD1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AMPD1 is a key enzyme in the purine nucleotide cycle that catalyzes the deamination of adenosine monophosphate (AMP) to inosine monophosphate (IMP), releasing ammonia as a byproduct. AMPD1 is primarily expressed in skeletal muscle and plays a critical role in energy metabolism by regulating adenine nucleotide levels during high-energy demands such as intense exercise. This activity helps replenish ATP levels through the recycling of IMP and promotes the balance of cellular energy homeostasis. Mutations in the AMPD1 gene can lead to AMP deaminase deficiency, also known as myoadenylate deaminase deficiency (MADD), a metabolic disorder characterized by muscle weakness, fatigue, and exercise intolerance. AMPD1 deficiency affects ATP production and disrupts normal purine metabolism, although many individuals remain asymptomatic. AMPD1 is also implicated in conditions like metabolic myopathies and has been studied for its role in enhancing exercise recovery and performance. Its regulation of energy metabolism highlights its importance in maintaining muscle function under stress.
Características del producto
category
ELISA Kits
immunogen target
AMP deaminase 1 (AMPD1)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Myoadenylate deaminase
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AMPD1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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