Human Alpha Synuclein (SNCA) Protein (Active)
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Description
Alpha Synuclein Protein (Active) is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Alpha Synuclein (SNCA) |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 14.46 kDa Sequence Fragment: Full Length |
| Expression | Recombinant |
| Purity | > 95% |
| Purification | Ion-exchange Purified |
| Size 1 | 100 µg |
| Tested Applications | WB, SDS-PAGE |
| Buffer | PBS pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at -80°C. |
| Dry Ice | Yes |
| UniProt ID | P37840 |
| Gene ID | 6622 |
| NCBI Accession | NP_000336.1 |
| Alias | SNCA |
| Background | Protein SNCA |
| Status | RUO |
| Note | This product is for research use only. This product is shipped with dry ice. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
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Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
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