Human Alpha 1 Microglobulin (AMBP) Protein

Product specifications

Proteins and Peptides

Alpha 1 Microglobulin (AMBP)

Human

Optimal dilutions/concentrations should be determined by the end user.

Human

Unconjugated

1 mg

Lyophilized 

ELISA

Prior to lyophilization: Ammonium bicarbonate

Shipped within 3-7 working days.

Store at -20 °C after reconstitution. Avoid repeated freeze/thaw cycles.

No

P02760

A1M,HCP,ITI,UTI,EDC1,HI30,ITIL,IATIL,ITILC,AMBP

Protein AMBP

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Alpha-1-Microglobulin-Bikunin Precursor (AMBP) encodes a precursor protein that generates two distinct products: alpha-1-microglobulin (A1M) and bikunin. Alpha-1-microglobulin is a small glycoprotein with potent antioxidant and anti-inflammatory properties, primarily involved in scavenging free heme and protecting tissues from oxidative stress and protein damage. It also binds and removes oxidized molecules, maintaining cellular homeostasis. Bikunin, on the other hand, is a Kunitz-type protease inhibitor that regulates serine proteases, playing a key role in controlling inflammation and extracellular matrix stabilization. As part of the inter-alpha-trypsin inhibitor family, bikunin contributes to tissue repair and proteolytic balance. Both proteins are primarily produced in the liver and circulate in the blood, fulfilling complementary functions in tissue protection and repair. Dysregulation of AMBP expression has been implicated in liver diseases, chronic inflammation, and cancer, where disruptions in antioxidant defense, protease regulation, and extracellular matrix stability contribute to disease progression, highlighting its importance in maintaining physiological homeostasis.

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Protein AMBP (AMBP) Antibody

AMBP Antibody is a Rabbit Polyclonal antibody against AMBP. This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

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