Human Alpha-1-Acid Glycoprotein 2 (ORM2) Peptide (OVA)

442€ (100 µg)
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name
Human Alpha-1-Acid Glycoprotein 2 (ORM2) Peptide (OVA)
category
Proteins and Peptides
provider
Abbexa
reference
abx651268
tested applications
WB, SDS-PAGE
Description
Orosomucoid 2 Peptide (OVA) is a Human protein conjugated to OVA.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Alpha-1-Acid Glycoprotein 2 (ORM2) |
Origin | Human |
Conjugation | OVA |
Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val106-Phe121 |
Expression | Synthetic |
Purity | > 90% |
Size 1 | 100 µg |
Size 2 | 200 µg |
Size 3 | 500 µg |
Size 4 | 1 mg |
Size 5 | 5 mg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | AGP2,AGP-B,AGP-B,Orosomucoid 2,OMD 2,Orosomucoid-2 |
Background | Protein ORM2 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Alpha-1-acid glycoprotein 2 (ORM2), also known as orosomucoid 2, is a major acute-phase protein predominantly produced in the liver and secreted into the bloodstream. ORM2 belongs to the lipocalin family, a group of small proteins characterized by their ability to bind and transport small hydrophobic molecules, including drugs, steroids, and lipids. As an acute-phase reactant, ORM2 levels increase significantly in response to inflammation, infection, trauma, or other physiological stresses, playing a critical role in the systemic inflammatory response.ORM2 is closely related to ORM1 (Alpha-1-acid glycoprotein 1), with both proteins sharing high sequence and structural homology. Together, they constitute the majority of the alpha-1-globulin fraction in human plasma. ORM2 has immunomodulatory functions, influencing immune cell activity, vascular permeability, and interactions between cytokines. Additionally, ORM2 is significant in pharmacology because it binds to various drugs, impacting their bioavailability and pharmacokinetics.
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ORM2 antibody
ORM2, also named as AGP2 and OMD 2, belongs to the calycin superfamily and Lipocalin family. It functions as transport protein in the blood stream. ORM2 binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability. ORM2 appears to function in modulating the activity of the immune system during the acute-phase reaction. ORM2 is one of the conserved endoplasmic reticulum membrane proteins which regulating lipid homeostasis and protein quality control. This antibody can recognize both ORM1 and ORM2.
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