Human Alpha-1-Acid Glycoprotein 2 (ORM2) Protein

Este producto es parte de ORM2 - Alpha-1-Acid Glycoprotein,type 2 (Orosomucoid 2)
Human Alpha-1-Acid Glycoprotein 2 (ORM2) Protein
325€ (20 µg)

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Name
Human Alpha-1-Acid Glycoprotein 2 (ORM2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx600022
Tested Applications
SDS-PAGE

Description

Human ORM2 Protein is a recombinant Protein produced in E.coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Alpha-1-Acid Glycoprotein 2 (ORM2)
Host
E. coli
Assay Type
Sequence Fragment: 19-201 aa
Tag: N-terminal 6 His tag
Origin
Human
Conjugation
Unconjugated
Observed MW
25.7 kDa
Expression
Recombinant
Purification
> 90% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Size 3
1 mg
Tested Applications
SDS-PAGE
Buffer
Tris-based buffer, 50% glycerol.
Availability
Shipped within 15-25 working days.
Storage
Store at -20 °C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P19652
Alias
AGP2,AGP-B,AGP-B,Orosomucoid 2,OMD 2,Orosomucoid-2
Background
Protein ORM2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Alpha-1-acid glycoprotein 2 (ORM2), also known as orosomucoid 2, is a major acute-phase protein predominantly produced in the liver and secreted into the bloodstream. ORM2 belongs to the lipocalin family, a group of small proteins characterized by their ability to bind and transport small hydrophobic molecules, including drugs, steroids, and lipids. As an acute-phase reactant, ORM2 levels increase significantly in response to inflammation, infection, trauma, or other physiological stresses, playing a critical role in the systemic inflammatory response.ORM2 is closely related to ORM1 (Alpha-1-acid glycoprotein 1), with both proteins sharing high sequence and structural homology. Together, they constitute the majority of the alpha-1-globulin fraction in human plasma. ORM2 has immunomodulatory functions, influencing immune cell activity, vascular permeability, and interactions between cytokines. Additionally, ORM2 is significant in pharmacology because it binds to various drugs, impacting their bioavailability and pharmacokinetics.

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