Human Alpha-1-Acid Glycoprotein 2 (ORM2) Protein

Product specifications

Proteins and Peptides

Alpha-1-Acid Glycoprotein 2 (ORM2)

E. coli

Human

Unconjugated

Molecular Weight: 25.7 kDa
Sequence Fragment: 19-201 aa
Tag: N-terminal 6 His tag
Validity: 6 months in liquid form, or 12 months in lyophilized form.

Recombinant

> 90% (SDS-PAGE)

10 µg

50 µg

100 µg

200 µg

500 µg

SDS-PAGE

Tris-based buffer, 50% glycerol.

Shipped within 1-2 months.

Store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.

No

P19652

AGP2,AGP-B,AGP-B,Orosomucoid 2,OMD 2,Orosomucoid-2

Protein ORM2

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Alpha-1-acid glycoprotein 2 (ORM2), also known as orosomucoid 2, is a major acute-phase protein predominantly produced in the liver and secreted into the bloodstream. ORM2 belongs to the lipocalin family, a group of small proteins characterized by their ability to bind and transport small hydrophobic molecules, including drugs, steroids, and lipids. As an acute-phase reactant, ORM2 levels increase significantly in response to inflammation, infection, trauma, or other physiological stresses, playing a critical role in the systemic inflammatory response.ORM2 is closely related to ORM1 (Alpha-1-acid glycoprotein 1), with both proteins sharing high sequence and structural homology. Together, they constitute the majority of the alpha-1-globulin fraction in human plasma. ORM2 has immunomodulatory functions, influencing immune cell activity, vascular permeability, and interactions between cytokines. Additionally, ORM2 is significant in pharmacology because it binds to various drugs, impacting their bioavailability and pharmacokinetics.

Related Products

Human ORM2(Alpha-1-acid glycoprotein 2) ELISA Kit

Ver Producto

Mouse ORM2(Orosomucoid 2) ELISA Kit

Ver Producto

anti- ORM2 antibody

ORM2, also named as AGP2 and OMD 2, belongs to the calycin superfamily and Lipocalin family. It functions as transport protein in the blood stream. ORM2 binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability. ORM2 appears to function in modulating the activity of the immune system during the acute-phase reaction. ORM2 is one of the conserved endoplasmic reticulum membrane proteins which regulating lipid homeostasis and protein quality control. This antibody can recognize both ORM1 and ORM2.

Ver Producto