Human ALDH4A1 (Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human ALDH4A1 (Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1722
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P30038 |
| Alias | P5C dehydrogenase |
| Background | Elisa kits for ALDH4A1 |
| Status | RUO |
Background
ALDH4A1, also known as pyrroline-5-carboxylate dehydrogenase (P5CDH), is a mitochondrial enzyme that catalyzes the conversion of pyrroline-5-carboxylate (P5C) into glutamate as part of the proline degradation pathway. This reaction is critical for maintaining amino acid metabolism, nitrogen balance, and cellular energy production. ALDH4A1 is expressed in tissues such as the liver, kidneys, and muscles, where proline serves as a key energy substrate. Mutations in ALDH4A1 lead to hyperprolinemia type II, a rare metabolic disorder characterized by elevated levels of proline and P5C, causing neurological symptoms, seizures, and cognitive impairments. ALDH4A1 also plays a role in protecting cells from oxidative stress, as proline metabolism generates NADH, which supports mitochondrial function. Its regulation is critical for amino acid catabolism, energy balance, and stress responses under nutrient deprivation.
Productos relacionados
Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) Antibody
ALDH4A1 Antibody is a Rabbit Polyclonal antibody against ALDH4A1. This protein belongs to the aldehyde dehydrogenase fam…
Ver producto
Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) Antibody
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent de…
Ver producto
Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) Antibody
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent de…
Ver producto