Human Alanine--TRNA Ligase, Cytoplasmic (AARS1) ELISA Kit
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Description
Human Alanyl tRNA Synthetase (AARS) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alanyl tRNA Synthetase (AARS) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alanine--TRNA Ligase, Cytoplasmic (AARS1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AARS1,AARS |
| Background | Elisa kits for AARS1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Alanine-tRNA ligase, encoded by the genes AARS1 (cytoplasmic) and AARS2 (mitochondrial), is a member of the aminoacyl-tRNA synthetase (aaRS) family. These enzymes are crucial for protein synthesis, catalyzing the attachment of alanine to its corresponding tRNA (tRNA^Ala) in a process known as tRNA aminoacylation. This reaction is an essential step in the translation process, ensuring accurate incorporation of alanine into nascent polypeptides according to the genetic code.AARS1 functions in the cytoplasm and is involved in general protein synthesis and AARS2 operates in mitochondria, where it is critical for mitochondrial protein synthesis, essential for maintaining respiratory chain function.The genes encoding these enzymes are conserved across species, reflecting their indispensable role in cellular physiology. Mutations in these genes are associated with various diseases, including neurodegenerative disorders, mitochondrial dysfunction, and cancer.
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