Human AF4/FMR2 Family, Member 1 (AFF1) Protein

Este producto es parte de AFF - AF4/FMR2 family member
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234€ (10 µg)

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935106861
info@markelab.com
name
Human AF4/FMR2 Family, Member 1 (AFF1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166951
tested applications
WB, SDS-PAGE

Description

AFF1 Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
AF4/FMR2 Family, Member 1 (AFF1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 24.2 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Met1-Gly183
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
AF4,FEL,MLLT2,PBM1
Background
Protein AFF1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

The AFF (AF4/FMR2) family member refers to a group of proteins associated with various cellular functions, particularly in the context of gene regulation and transcriptional control. The name "AFF" comes from the fusion partner of MLL (Mixed-Lineage Leukemia) in certain leukemia cases, where AFF1, also known as AF4, is one of the fusion partners. AFF1 (AF4) is a protein implicated in chromosomal translocations that result in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). It's known to be involved in transcriptional elongation and regulation. The AF4 protein itself is associated with the super elongation complex (SEC), which plays a role in regulating RNA polymerase II elongation.

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