Human AF4/FMR2 Family, Member 1 (AFF1) ELISA Kit

Este producto es parte de AFF - AF4/FMR2 family member
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715€ (96 tests)

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935106861
info@markelab.com
name
Human AF4/FMR2 Family, Member 1 (AFF1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150584
tested applications
ELISA

Description

Human AF4/FMR2 Family, Member 1 (AFF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human AFF1 concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of AFF1 (AFF1)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
AF4/FMR2 Family, Member 1 (AFF1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
AF4,FEL,MLLT2,PBM1
Background
Elisa kits for AFF1
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

The AFF (AF4/FMR2) family member refers to a group of proteins associated with various cellular functions, particularly in the context of gene regulation and transcriptional control. The name "AFF" comes from the fusion partner of MLL (Mixed-Lineage Leukemia) in certain leukemia cases, where AFF1, also known as AF4, is one of the fusion partners. AFF1 (AF4) is a protein implicated in chromosomal translocations that result in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). It's known to be involved in transcriptional elongation and regulation. The AF4 protein itself is associated with the super elongation complex (SEC), which plays a role in regulating RNA polymerase II elongation.

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