Human Adrenomedullin (ADM) Peptide (KLH)
1872€ (1 mg)
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935106861
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name
Human Adrenomedullin (ADM) Peptide (KLH)
category
Proteins and Peptides
provider
Abbexa
reference
abx165502
tested applications
WB, SDS-PAGE
Description
ADM Protein is a Human protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adrenomedullin (ADM) |
| Origin | Human |
| Conjugation | KLH |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml |
| Expression | Synthetic |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AM,PAMP |
| Background | Protein ADM |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Adrenomedullin (ADM) is a peptide hormone that is primarily secreted by various tissues, including the adrenal medulla, vascular endothelium, heart, lungs, and kidneys. Adrenomedullin is a 52-amino acid peptide hormone derived from a larger precursor protein called preproadrenomedullin. It belongs to the calcitonin gene-related peptide (CGRP) family and shares structural similarities with calcitonin and calcitonin gene-related peptide. Adrenomedullin plays a crucial role in regulating vascular tone, blood pressure, and cardiovascular homeostasis by promoting vasodilation and inhibiting vasoconstriction. Additionally, adrenomedullin exhibits anti-inflammatory, anti-apoptotic, and angiogenic properties, contributing to tissue protection and repair.Adrenomedullin binds to specific receptors known as adrenomedullin receptors (ADMR), which are coupled to G proteins
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