Human Adrenomedullin (ADM) CLIA Kit
845€ (96 tests)
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name
Human Adrenomedullin (ADM) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx490045
tested applications
CLIA
Description
Human Adrenomedullin (ADM) Chemiluminescent Immunoassay (CLIA) Kit is a Competitive Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Adrenomedullin (ADM) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Competitive |
| Test Range | 3.9 pg/ml - 1000 pg/ml |
| Sensitivity | < 1.87 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P35318 |
| Gene ID | 133 |
| OMIM | 103275 |
| Alias | AM,PAMP |
| Background | CLIA Kits ADM |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Adrenomedullin (ADM) is a peptide hormone that is primarily secreted by various tissues, including the adrenal medulla, vascular endothelium, heart, lungs, and kidneys. Adrenomedullin is a 52-amino acid peptide hormone derived from a larger precursor protein called preproadrenomedullin. It belongs to the calcitonin gene-related peptide (CGRP) family and shares structural similarities with calcitonin and calcitonin gene-related peptide. Adrenomedullin plays a crucial role in regulating vascular tone, blood pressure, and cardiovascular homeostasis by promoting vasodilation and inhibiting vasoconstriction. Additionally, adrenomedullin exhibits anti-inflammatory, anti-apoptotic, and angiogenic properties, contributing to tissue protection and repair.Adrenomedullin binds to specific receptors known as adrenomedullin receptors (ADMR), which are coupled to G proteins
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