Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18 (ADAMTS18) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
585€ (96 tests)
Elisa kits for ADAMTS18
proveedor
Abbexareference
abx251648Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18 (ADAMTS18) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18 (ADAMTS18) concentrations in serum, plasma and other biological fluids.
Background
ADAMTS18, also known as ADAM metallopeptidase with thrombospondin type 1 motif 18, is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family of proteins. ADAMTS18 contains several distinct domains, including a metalloproteinase domain responsible for its proteolytic activity, as well as multiple thrombospondin type-1 (TSP-1) motifs. These motifs are believed to be involved in protein-protein interactions and may mediate interactions with other extracellular matrix components.ADAMTS18 is expressed in various tissues throughout the body, including the brain, heart, lung, liver, and kidney, suggesting its involvement in multiple physiological processes.Mutations or dysregulation of ADAMTS18 have been implicated in various diseases and disorders. For example, mutations in the ADAMTS18 gene have been linked to autosomal recessive congenital myopia, a condition characterized by severe nearsightedness present from birth. Additionally, alterations in ADAMTS18 expression have been observed in cancers, such as breast cancer and colorectal cancer, suggesting a potential role in tumorigenesis and tumor progression.
Características del producto
category
ELISA Kits
immunogen target
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18 (ADAMTS18)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
KNO2, MMCAT,ADAMTS21,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 18,ADAMTS-18,ADAM-TS18
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADAMTS18
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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