Human ADAM DEC1 (ADAMDEC1) Protein
273€ (10 µg)
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Name
Human ADAM DEC1 (ADAMDEC1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx690102
Tested Applications
SDS-PAGE
Description
ADAM DEC1 (ADAMDEC1) protein is a recombinant Human protein expressed in HEK293 cells.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | ADAM DEC1 (ADAMDEC1) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Lys206-Glu470 Tag: C-terminal 6 His tag |
| Origin | Human |
| Observed MW | Calculated MW: 30.3 kDa Observed MW (SDS-PAGE): 33-41 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | 0.2 µm filtered. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris-HCl, 150 mM NaCl, pH 7.5. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. Shelf Life: 6 months. |
| Dry Ice | No |
| UniProt ID | O15204 |
| Gene ID | 27299 |
| OMIM | 606393 |
| Alias | ADAM DEC1 |
| Background | Protein ADAMDEC1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
ADAM Like Decysin 1 (ADAMDEC1) is a member of the ADAM (a disintegrin and metalloprotease) family of proteins, which are involved in proteolysis and cell-cell or cell-matrix interactions. Unlike most ADAM proteins, ADAMDEC1 lacks a transmembrane domain, making it a secreted protein. It is primarily expressed in immune-related tissues, such as lymph nodes, the colon, and macrophages, where it is thought to participate in immune response regulation and extracellular matrix remodeling. ADAMDEC1 is involved in degrading extracellular matrix proteins, potentially playing a role in inflammation, tissue remodeling, and immune surveillance. Dysregulation of ADAMDEC1 has been associated with inflammatory conditions and cancer, where altered extracellular matrix remodeling contributes to tumor invasion and metastasis. Emerging research focuses on its role in modulating immune cell activity and its potential as a biomarker or therapeutic target in inflammatory and oncological diseases.
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