Human Acyl Coenzyme A Dehydrogenase, C2-To-C3 Short Chain (ACADS) Protein

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Description
Human ACADS Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Acyl Coenzyme A Dehydrogenase, C2-To-C3 Short Chain (ACADS) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 23.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile210-Glu396 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P16219 |
Alias | acyl-CoA dehydrogenase C-2 to C-3 short chain,ACAD3,SCAD,Butyryl-CoA Dehydrogenase |
Background | Protein ACADS |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
The ACADS gene encodes the enzyme acyl-CoA dehydrogenase short chain, a tetrameric mitochondrial flavoprotein involved in the initial step of the mitochondrial fatty acid beta-oxidation pathway. This enzyme belongs to the acyl-CoA dehydrogenase family and is crucial for metabolizing short-chain fatty acids. Mutations in the ACADS gene have been linked to short-chain acyl-CoA dehydrogenase (SCAD) deficiency, a metabolic disorder. Alternative splicing of this gene produces two variants encoding different isoforms of the enzyme.
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