Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACSF3
proveedor
Abbexareference
abx500873Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACSF3 is a mitochondrial acyl-CoA synthetase responsible for the activation of malonic and methylmalonic acids, essential steps in the metabolism of certain fatty acids and amino acids. Its primary function is to facilitate the incorporation of these intermediates into metabolic pathways such as the tricarboxylic acid (TCA) cycle and gluconeogenesis. ACSF3 is highly expressed in the liver and skeletal muscle, where it supports energy homeostasis and metabolic flexibility by processing odd-chain fatty acids and branched-chain amino acids. Mutations in the ACSF3 gene are associated with combined malonic and methylmalonic aciduria, a rare metabolic disorder characterized by the accumulation of malonic acid and methylmalonic acid, leading to metabolic acidosis and developmental delays. By regulating these metabolic intermediates, ACSF3 plays a crucial role in preventing the buildup of toxic metabolites and ensuring efficient energy production under metabolic stress conditions.
Características del producto
category
ELISA Kits
immunogen target
Acyl-CoA synthetase family member 3, mitochondrial (ACSF3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ACSF3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACSF3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Acyl-CoA Synthetase Family Member 3 (ACSF3) Antibody

proveedor
Abbexareference
abx037402Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalRabbit Polyclonal against the ACSF3 protein.
357.5€ (100 µg)
Ver másAcyl-CoA Synthetase Family Member 3 (ACSF3) Antibody

proveedor
Abbexareference
abx313405Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalACSF3 Antibody is a Rabbit Polyclonal against ACSF3.
169€ (20 µg)
Ver másAcyl-CoA Synthetase Family Member 3 (ACSF3) Antibody (HRP)

proveedor
Abbexareference
abx313406Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalACSF3 Antibody (HRP) is a Rabbit Polyclonal against ACSF3 conjugated to HRP.
169€ (20 µg)
Ver más