Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) ELISA Kit

Este producto es parte de ACSF - Acyl-CoA Synthetase Family Member
Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500873
tested applications
ELISA

Description

Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-CoA synthetase family member 3, mitochondrial (ACSF3) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Acyl-CoA synthetase family member 3, mitochondrial (ACSF3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q4G176
Alias
ACSF3
Background
Elisa kits for ACSF3
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ACSF3 is a mitochondrial acyl-CoA synthetase responsible for the activation of malonic and methylmalonic acids, essential steps in the metabolism of certain fatty acids and amino acids. Its primary function is to facilitate the incorporation of these intermediates into metabolic pathways such as the tricarboxylic acid (TCA) cycle and gluconeogenesis. ACSF3 is highly expressed in the liver and skeletal muscle, where it supports energy homeostasis and metabolic flexibility by processing odd-chain fatty acids and branched-chain amino acids. Mutations in the ACSF3 gene are associated with combined malonic and methylmalonic aciduria, a rare metabolic disorder characterized by the accumulation of malonic acid and methylmalonic acid, leading to metabolic acidosis and developmental delays. By regulating these metabolic intermediates, ACSF3 plays a crucial role in preventing the buildup of toxic metabolites and ensuring efficient energy production under metabolic stress conditions.

Related Products

P9077

Recombinant Human ACSF3

Ver Producto
abx037402

Acyl-CoA Synthetase Family Member 3 (ACSF3) Antibody

Rabbit Polyclonal against the ACSF3 protein.

Ver Producto
abx313405

Acyl-CoA Synthetase Family Member 3 (ACSF3) Antibody

ACSF3 Antibody is a Rabbit Polyclonal against ACSF3.

Ver Producto