Human Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Protein
234€ (2 µg)
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935106861
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name
Human Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073777
tested applications
SDS-PAGE
Description
ACADM Protein is a recombinant enzyme.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11310 |
| Alias | ACAD1,MCAD,MCADH |
| Background | Protein ACADM |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.
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