Human Activator Of 90 KDa Heat Shock Protein ATPase Homolog 1 (AHSA1) Protein
455€ (50 µg)
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Name
Human Activator Of 90 KDa Heat Shock Protein ATPase Homolog 1 (AHSA1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx675031
Tested Applications
WB, SDS-PAGE
Description
AHA1 Protein is a protein produced in Human.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Activator Of 90 KDa Heat Shock Protein ATPase Homolog 1 (AHSA1) |
| Host | E. coli |
| Origin | Human |
| Observed MW | 38 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Tested Applications | WB, SDS-PAGE |
| Buffer | 20 mM HEPES buffer pH7.2, 80 mM NaCl, 10% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at -20 °C. |
| Dry Ice | No |
| UniProt ID | O95433 |
| Gene ID | 10598 |
| NCBI Accession | NP_036243.1 |
| Alias | AHA1, C14orf3, hAha1, p38 |
| Background | Protein AHSA1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
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