Human Actin Filament Associated Protein 1 (AFAP1) ELISA Kit

Este producto es parte de AFAP - Actin Filament Associated Protein 1 (Like )
Human Actin Filament Associated Protein 1 (AFAP1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

611€ (96 tests)

Elisa kits for AFAP1

proveedor

Abbexa

reference

abx354304

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Actin Filament Associated Protein 1 (AFAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Actin Filament Associated Protein 1 (AFAP1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Actin Filament Associated Protein 1 (AFAP1), also known as AFAP-110 or AFAP1L1, is a cytoskeletal protein involved in the regulation of actin dynamics and cell motility. AFAP1 is a multidomain protein consisting of several functional domains, including an N-terminal BAR (Bin-Amphiphysin-Rvs) domain, a central proline-rich region, a serine-rich region, and a C-terminal SH3 (Src homology 3) domain. These domains facilitate protein-protein interactions and mediate the binding of AFAP1 to various cytoskeletal and signaling molecules. AFAP1 regulates actin cytoskeleton dynamics by interacting with actin filaments and modulating their organization and stability. It can promote actin polymerization and bundling, as well as cross-linking of actin filaments, thereby influencing cell shape, migration, and adhesion. AFAP1 also plays a role in cell motility and migration by coordinating actin cytoskeleton rearrangements necessary for cell protrusion, adhesion, and movement. It interacts with signaling proteins involved in focal adhesion turnover, cytoskeletal remodeling, and cell contractility

Características del producto

category

ELISA Kits


immunogen target

Actin Filament Associated Protein 1 (AFAP1)


reactivity

Human


test range

0.78 ng/ml - 50 ng/ml


sensitivity

0.47 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

AFAP,AFAP110,AFAP-110


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AFAP1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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