Human Aconitase 2 (ACO2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for ACO2
proveedor
Abbexareference
abx354303Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Aconitase 2 (ACO2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aconitase 2 (ACO2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Aconitase 2 (ACO2) is a mitochondrial enzyme involved in the tricarboxylic acid (TCA) cycle, where it catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. ACO2 is essential for cellular energy production, linking carbohydrate metabolism to the production of reducing equivalents such as NADH and FADH2. The enzyme contains an iron-sulfur cluster that is critical for its catalytic activity but also makes it sensitive to oxidative damage, which can impair function. Mutations or dysregulation of ACO2 are associated with mitochondrial diseases, neurodegenerative disorders such as Parkinson's disease, and aging, as oxidative stress often leads to loss of aconitase activity. ACO2 is also being explored as a biomarker for mitochondrial dysfunction in metabolic and neurological conditions.
Características del producto
category
ELISA Kits
immunogen target
Aconitase 2 (ACO2)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ICRD,OCA8,OPA9,ACONM,HEL-S-284
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACO2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Human ACO2(Aconitase 2) ELISA Kit
proveedor
FineTestreference
EH6071reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse Aco2(Aconitate hydRatase, mitochondrial) ELISA Kit
proveedor
FineTestreference
EM0559reactivity
mousestatus
RUOPrecio a consultar
Ver másRat Aco2(Aconitate hydRatase, mitochondrial) ELISA Kit
proveedor
FineTestreference
ER0486reactivity
ratstatus
RUOPrecio a consultar
Ver más