Human Acetyl Coenzyme A Acetyltransferase 2 (ACAT2) CLIA Kit
643.5€ (96 tests)
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name
Human Acetyl Coenzyme A Acetyltransferase 2 (ACAT2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195531
tested applications
CLIA
Description
Human Acetyl Coenzyme A Acetyltransferase 2, cytosolic (ACAT2) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Acetyl Coenzyme A Acetyltransferase 2, cytosolic (ACAT2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Acetyl Coenzyme A Acetyltransferase 2 (ACAT2) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ACAT2,Sterol O-acyltransferase 2 |
| Background | CLIA Kits ACAT2 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACAT2 is a cytosolic enzyme that is primarily expressed in the liver and intestine and is responsible for the esterification of cholesterol with long-chain fatty acids to form cholesteryl esters, which are then incorporated into lipoproteins such as very-low-density lipoproteins (VLDL) and chylomicrons. Unlike ACAT1, which is involved in mitochondrial ketone metabolism, ACAT2 plays a pivotal role in cholesterol homeostasis and lipid transport. It is essential for the packaging of cholesterol for transport through the bloodstream and is therefore crucial for maintaining lipid balance. Dysregulation of ACAT2 activity is associated with hypercholesterolemia and atherosclerosis, as increased cholesteryl ester formation can contribute to the formation of atherosclerotic plaques. Targeting ACAT2 has been explored as a potential therapeutic approach for reducing cholesterol levels and cardiovascular disease risk.
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