Human Acetyl Coenzyme A Acetyltransferase 1 (ACAT1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACAT1
proveedor
Abbexareference
abx253756Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Acetyl Coenzyme A Acetyltransferase 1 (ACAT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acetyl Coenzyme A Acetyltransferase 1 (ACAT1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACAT1, also known as mitochondrial acetoacetyl-CoA thiolase, is an enzyme localized in the mitochondria that catalyzes the reversible conversion of two molecules of acetyl-CoA into acetoacetyl-CoA, a critical step in ketone body synthesis and cholesterol metabolism. It is involved in energy production during periods of fasting or carbohydrate restriction by contributing to ketogenesis. ACAT1 also plays a role in the breakdown of branched-chain amino acids, linking it to amino acid metabolism. Dysregulation or mutations in the ACAT1 gene have been implicated in rare metabolic disorders such as beta-ketothiolase deficiency, which is characterized by the inability to properly metabolize ketogenic amino acids and fatty acids, leading to metabolic acidosis. Recent studies have also suggested a potential role for ACAT1 in cancer metabolism, where its activity is linked to metabolic reprogramming in tumor cells.
Características del producto
category
ELISA Kits
immunogen target
Acetyl Coenzyme A Acetyltransferase 1 (ACAT1)
reactivity
Human
test range
7.8 pg/ml - 500 pg/ml
sensitivity
< 3.5 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ACAT,MAT,T2,THIL,Acetoacetyl-CoA thiolase
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACAT1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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