Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit

Este producto es parte de ACAA - Acetyl Coenzyme A Acyltransferase
Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit
715€ (96 tests)

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Name
Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx385564
Tested Applications
ELISA

Description

Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acetyl-CoA Acetyltransferase 1 (ACAA1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Acetyl-CoA Acetyltransferase 1 (ACAA1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.313 ng/ml - 20 ng/ml
Sensitivity
< 0.188 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P09110
Gene ID
30
OMIM
604054
Alias
ACAA, Lnc-Myd88, PTHIO, THIO
Background
Elisa Kits for: ACAA1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Acetyl Coenzyme A Acyltransferase 1 (ACAA1), also known as thiolase, is a peroxisomal enzyme involved in the final step of beta-oxidation of very-long-chain fatty acids and branched-chain fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA and a shortened acyl-CoA, which is then further metabolized for energy production. ACAA1 is critical for lipid metabolism and plays an important role in energy homeostasis during fasting or periods of high energy demand. Dysregulation of ACAA1 activity can lead to metabolic disorders, such as Zellweger syndrome and other peroxisomal biogenesis disorders, characterized by impaired fatty acid oxidation and accumulation of toxic lipid intermediates. ACAA1 is also being studied for its role in the metabolic reprogramming of cancer cells, where it contributes to lipid catabolism and tumor progression.

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