Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit

Este producto es parte de ACAA - Acetyl Coenzyme A Acyltransferase
Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ACAA1

proveedor

Abbexa

reference

abx385564

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acetyl-CoA Acetyltransferase 1 (ACAA1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Acetyl Coenzyme A Acyltransferase 1 (ACAA1), also known as thiolase, is a peroxisomal enzyme involved in the final step of beta-oxidation of very-long-chain fatty acids and branched-chain fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA and a shortened acyl-CoA, which is then further metabolized for energy production. ACAA1 is critical for lipid metabolism and plays an important role in energy homeostasis during fasting or periods of high energy demand. Dysregulation of ACAA1 activity can lead to metabolic disorders, such as Zellweger syndrome and other peroxisomal biogenesis disorders, characterized by impaired fatty acid oxidation and accumulation of toxic lipid intermediates. ACAA1 is also being studied for its role in the metabolic reprogramming of cancer cells, where it contributes to lipid catabolism and tumor progression.

Características del producto

category

ELISA Kits


immunogen target

Acetyl-CoA Acetyltransferase 1 (ACAA1)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

ACAA, Lnc-Myd88, PTHIO, THIO


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ACAA1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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