Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACAA1
proveedor
Abbexareference
abx385564Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Acetyl-CoA Acetyltransferase 1 (ACAA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acetyl-CoA Acetyltransferase 1 (ACAA1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Acetyl Coenzyme A Acyltransferase 1 (ACAA1), also known as thiolase, is a peroxisomal enzyme involved in the final step of beta-oxidation of very-long-chain fatty acids and branched-chain fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA and a shortened acyl-CoA, which is then further metabolized for energy production. ACAA1 is critical for lipid metabolism and plays an important role in energy homeostasis during fasting or periods of high energy demand. Dysregulation of ACAA1 activity can lead to metabolic disorders, such as Zellweger syndrome and other peroxisomal biogenesis disorders, characterized by impaired fatty acid oxidation and accumulation of toxic lipid intermediates. ACAA1 is also being studied for its role in the metabolic reprogramming of cancer cells, where it contributes to lipid catabolism and tumor progression.
Características del producto
category
ELISA Kits
immunogen target
Acetyl-CoA Acetyltransferase 1 (ACAA1)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.188 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ACAA, Lnc-Myd88, PTHIO, THIO
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACAA1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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