Human Acetoacetyl-CoA Synthetase (AACS) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AACS
proveedor
Abbexareference
abx385531Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Acetoacetyl-CoA Synthetase (AACS) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acetoacetyl Coenzyme A Synthetase (AACS) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The acetoacetyl-CoA synthetase (AACS) gene encodes a protein of the same name, which converts acetoacetate to acetoacetyl-CoA, and plays a crucial role in ketone body utilization and fatty acid synthesis. The gene is found on human chromosome 12. Ketone bodies, unlike fatty acids and triglycerides, are water-soluble. They are exported from the liver, and are taken up by other tissues, notably brain and skeletal and cardiac muscle. There, they are broken down to acetyl-CoA which is oxidized via the TCA cycle to yield energy. In a normal person, this pathway of ketone body synthesis and utilization is most active during extended periods of fasting. Under these conditions, mobilization and breakdown of stored fatty acids generates abundant acetyl-CoA acetyl-CoA in liver cells for synthesis of ketone bodies, and their utilization in other tissues minimizes the demand of these tissues for glucose
Características del producto
category
ELISA Kits
immunogen target
Acetoacetyl-CoA Synthetase (AACS)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ACSF1,SUR-5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AACS
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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