Horse Cartilage Oligomeric Matrix Protein (COMP) CLIA Kit
884€ (96 tests)
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935106861
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name
Horse Cartilage Oligomeric Matrix Protein (COMP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx496636
tested applications
CLIA
Description
Horse Cartilage Oligomeric Matrix Protein (COMP) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) Kit against Cartilage Oligomeric Matrix Protein (COMP).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Cartilage Oligomeric Matrix Protein (COMP) |
| Reactivity | Horse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 46.88 pg/ml - 3000 pg/ml |
| Sensitivity | < 18.56 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | MED,CTS2,EDM1,EPD1,TSP5,PSACH,THBS5,TSP-5,Thrombospondin-5 |
| Background | CLIA Kits COMP |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
COMP is a non-collagenous extracellular matrix protein primarily expressed in cartilage, tendons, and ligaments where it plays a key role in maintaining tissue structure and mechanical integrity COMP interacts with collagen fibrils and other matrix components to facilitate fibril assembly and stabilize the extracellular matrix COMP also functions as a chaperone during collagen secretion, promoting proper folding and export from chondrocytes Mutations in COMP are associated with skeletal dysplasias such as pseudoachondroplasia and multiple epiphyseal dysplasia, which result in abnormal cartilage development, joint pain, and short stature COMP overexpression has been observed in osteoarthritis and rheumatoid arthritis, where its elevated levels contribute to cartilage degradation and inflammation COMP is also implicated in cardiovascular diseases where it regulates vascular smooth muscle cell function and extracellular matrix remodeling
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