CD44 Antigen (CD44) Antibody (Cyanine 3)

Product specifications

Primary Antibodies

CD44 Antigen (CD44)

Rabbit

Human

IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Cyanine 3

IgG

Purified by antigen-specific affinity chromatography.

200 µl

1 ml

Liquid

IHC, IF/ICC

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.

Shipped within 5-15 working days.

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.

No

IN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor

Antibody anti-CD44

RUO

Descripción

CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.

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