CD44 Antigen (CD44) Antibody

273€ (100 µl)
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935106861
info@markelab.com
name
CD44 Antigen (CD44) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx172837
tested applications
WB, IHC, IF/ICC
Description
CD44 Antigen (CD44) Antibody is a Mouse Monoclonal antibody against CD44 Antigen (CD44).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | CD44 Antigen (CD44)  | 
| Host | Mouse  | 
| Reactivity | Human  | 
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Monoclonal  | 
| Conjugation | Unconjugated  | 
| Purification | Purified by Protein A and Protein G affinity chromatography.  | 
| Size 1 | 100 µl  | 
| Size 2 | 200 µl  | 
| Size 3 | 1 ml  | 
| Form | Liquid  | 
| Tested Applications | WB, IHC, IF/ICC  | 
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.  | 
| Availability | Shipped within 5-7 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| Alias | IN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor  | 
| Background | Antibody anti-CD44  | 
| Status | RUO  | 
Descripción
CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.
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