HNF4 alpha / gamma Cell ELISA Kit
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935106861
info@markelab.com
Precio
493.75€ (96 tests)
Elisa Kits HNF4A
proveedor
Abbexareference
abx595751Tested Applications
ELISAreactivity
Human, Mouse, Ratstatus
RUOclonality
Descripción
HNF4 alpha/gamma Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Background
Hepatocyte nuclear factor 4 alpha (HNF4A) is a critical transcription factor that plays a key role in regulating liver function, metabolism, and the development of the gastrointestinal tract HNF4A is highly expressed in the liver, where it controls the expression of genes involved in hepatic glucose production, lipid metabolism, and bile acid synthesis It also regulates the development and differentiation of liver cells and contributes to maintaining liver homeostasis HNF4A is involved in controlling genes responsible for the metabolism of steroids, carbohydrates, and lipids, and it is crucial for maintaining the liver's metabolic functions Dysregulation of HNF4A has been associated with metabolic diseases, such as diabetes, non-alcoholic fatty liver disease (NAFLD), and liver cirrhosis In addition, mutations in the HNF4A gene can lead to maturity-onset diabetes of the young (MODY), a form of diabetes characterized by early-onset, autosomal dominant inheritance of insulin resistance
Características del producto
category
ELISA Kits
immunogen target
HNF4 alpha/gamma
reactivity
Human, Mouse, Rat
detection method
Colorimetric
sample type
Cell ELISA
size 1
96 tests
alias
TCF,HNF4,MODY,FRTS4,MODY1,NR2A1,TCF14,HNF4a7,HNF4a8,HNF4a9,NR2A21,TCF-14,HNF4alpha,Transcription factor HNF-4,Nuclear receptor subfamily 2 group A member 1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
HNF4A
dry ice
No
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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