Histone-Lysine N-Methyltransferase SETD7 (SETD7) Antibody

Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Histone-Lysine N-Methyltransferase SETD7 (SETD7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302812
tested applications
ELISA, WB, IHC

Description

Histone-Lysine N-Methyltransferase SETD7 (SETD7) Antibody is a Rabbit Polyclonal against Histone-Lysine N-Methyltransferase SETD7 (SETD7).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Histone-Lysine N-Methyltransferase SETD7 (SETD7)
Immunogen: Recombinant human Histone-lysine N-methyltransferase SETD7 protein (1-366AA).
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8WTS6
Gene ID
80854
OMIM
606594
Background
Antibody anti-SETD7
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Related Products

FNab07769

SETD7 antibody

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Ver Producto
P6258

Recombinant Human SETD7

Ver Producto
abx073929

Human SET Domain Containing Protein 7 (SETD7) Protein

Set7/9 Histone Methyltransferase is a recombinant enzyme.

Ver Producto