Histone H4K20me2 Antibody

Histone H4K20me2 Antibody
208€ (20 µl)

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Name
Histone H4K20me2 Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000018
Tested Applications
ELISA, WB, IHC, IF/ICC

Description

Histone H4K20me2 Antibody is a Rabbit Polyclonal antibody against Histone H4K20me2. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Histone H4K20me2
Immunogen: Synthetic peptide corresponding to Histone H4K20me2. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 11 kDa  Observed MW: 11 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P62805
Gene ID
8370
NCBI Accession
NP_003529.1
Background
Antibody anti-Histone
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.