Histone Deacetylase 4 (HDAC4) Antibody

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Description
HDAC4 Antibody is a Mouse Monoclonal against HDAC4.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Histone Deacetylase 4 (HDAC4) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Isotype | IgG1 |
Purification | Purified from ascites by Protein G chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC, FCM |
Buffer | PBS, containing 0.05% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P56524 |
Gene ID | 9759 |
OMIM | 600430 |
Background | Antibody anti-HDAC4 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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