Histone Deacetylase 3 (HDAC3) Antibody

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Description
HDAC3 Antibody is a Mouse Monoclonal antibody against HDAC3.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Histone Deacetylase 3 (HDAC3) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Purification | Purified from ascites by Protein A chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
NCBI Accession | NM_003883 |
Background | Antibody anti-HDAC3 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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