Histone Deacetylase 3 (HDAC3) Antibody

Descripción

HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2.Entrez Protein NC_000005.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family.It has histone deacetylase activity and represses transcription when tethered to a promoter.It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.This gene is regarded as a potential tumor suppressor gene.