Histone Chaperone ASF1A (ASF1A) Antibody
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Description
ASF1A Antibody is a Rabbit Polyclonal antibody against ASF1A. This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The protein is a key component of a histone donor complex that functions in nucleosome assembly. It interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Histone Chaperone ASF1A (ASF1A) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y294 |
| Gene ID | 25842 |
| NCBI Accession | NP_054753.1 |
| Alias | ASF1A,CGI-98,HSPC146,Anti-silencing function protein 1 homolog A |
| Background | Antibody anti-ASF1A |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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ASF1A antibody
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1(CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci(SAHF) and efficient senescence-associated cell cycle exit.
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Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1(CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci(SAHF) and efficient senescence-associated cell cycle exit.
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