Histone-Binding Protein RBBP7 (RBBP7) Antibody
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Description
Histone-Binding Protein RBBP7 (RBBP7) Antibody is a Rabbit polyclonal antibody for the detection of Human Histone-Binding Protein RBBP7 (RBBP7).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Histone-Binding Protein RBBP7 (RBBP7) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q16576 |
| Gene ID | 5931 |
| NCBI Accession | NP_001185648.1 |
| Background | Antibody anti-RBBP7 |
| Status | RUO |
Descripción
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This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
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