Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237743
tested applications
ELISA, WB, IHC, IF/ICC
Description
SERPINB10 Antibody is a Rabbit Polyclonal against SERPINB10.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Heterochromatin-Associated Protein MENT (SERPINB10) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48595 |
| Gene ID | 5273 |
| OMIM | 602058 |
| Alias | PI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10 |
| Background | Antibody anti-SERPINB10 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.
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