Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
377€ (100 µg)
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Name
Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx237743
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
SERPINB10 Antibody is a Rabbit Polyclonal against SERPINB10.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Heterochromatin-Associated Protein MENT (SERPINB10) Immunogen: serpin peptidase inhibitor, clade B(ovalbumin), member 10 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 45 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48595 |
| Gene ID | 5273 |
| OMIM | 602058 |
| Alias | PI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10 |
| Background | Antibody anti-SERPINB10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.
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