Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody
299€ (50 µl)
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935106861
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name
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx402566
tested applications
ELISA, WB
Description
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human, Mouse HAVCR1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Hepatitis A Virus Cellular Receptor 1 (HAVCR1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96D42 |
| Alias | Kidney injury molecule 1,TIM,KIM1,TIM1,CD365,HAVCR,KIM-1,TIM-1,TIMD1,TIMD-1,HAVCR-1,T-cell immunoglobulin and mucin domain-containing protein 1,T-cell immunoglobulin mucin receptor 1,T-cell membrane protein 1 |
| Background | Antibody anti-HAVCR1 |
| Status | RUO |
Descripción
Hepatitis A Virus Cellular Receptor 1 (HAVCR1), also known as TIM-1 (T-cell immunoglobulin and mucin domain-containing protein 1), is a receptor protein expressed primarily on the surface of kidney epithelial cells and various immune cells. It is a member of the TIM family of proteins, which includes other receptors like TIM-3 and TIM-4. HAVCR1 plays a critical role in immune regulation, cell signaling, and disease pathogenesis, particularly within inflammatory and immune-mediated conditions. Initially identified as the receptor for hepatitis A virus (HAV), HAVCR1 has since been associated with numerous physiological and pathological processes, including immune cell activation, tissue inflammation, and the regulation of T-cell responses. HAVCR1 is implicated in immune tolerance and modulation of immune responses, making it relevant in autoimmune disorders, infections, and cancer.
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