Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody

Este producto es parte de HAVCR1 - hepatitis A virus cellular receptor 1
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169€ (20 µg)

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935106861
info@markelab.com
name
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx318372
tested applications
ELISA, WB, IHC

Description

HAVCR1 Antibody is a Rabbit Polyclonal against HAVCR1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Hepatitis A Virus Cellular Receptor 1 (HAVCR1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96D42
Gene ID
26762
OMIM
606518
Alias
Kidney injury molecule 1,TIM,KIM1,TIM1,CD365,HAVCR,KIM-1,TIM-1,TIMD1,TIMD-1,HAVCR-1,T-cell immunoglobulin and mucin domain-containing protein 1,T-cell immunoglobulin mucin receptor 1,T-cell membrane protein 1
Background
Antibody anti-HAVCR1
Status
RUO

Descripción

Hepatitis A Virus Cellular Receptor 1 (HAVCR1), also known as TIM-1 (T-cell immunoglobulin and mucin domain-containing protein 1), is a receptor protein expressed primarily on the surface of kidney epithelial cells and various immune cells. It is a member of the TIM family of proteins, which includes other receptors like TIM-3 and TIM-4. HAVCR1 plays a critical role in immune regulation, cell signaling, and disease pathogenesis, particularly within inflammatory and immune-mediated conditions. Initially identified as the receptor for hepatitis A virus (HAV), HAVCR1 has since been associated with numerous physiological and pathological processes, including immune cell activation, tissue inflammation, and the regulation of T-cell responses. HAVCR1 is implicated in immune tolerance and modulation of immune responses, making it relevant in autoimmune disorders, infections, and cancer.

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