Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) Antibody
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Description
Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) Antibody is a Rabbit polyclonal antibody for the detection of Human Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7LGA3 |
| Gene ID | 9653 |
| NCBI Accession | NP_001127964.1 |
| Background | Antibody anti-HS2ST1 |
| Status | RUO |
Descripción
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Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate(HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues(By similarity).
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Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) Antibody
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Heparan sulfate 2-O-sulfotransferase is a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of the HS2ST1 gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
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Rabbit Polyclonal against the HS2ST1 protein.
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