Hemoglobin Subunit Epsilon (HBE1) Antibody

312€ (60 µl)
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name
Hemoglobin Subunit Epsilon (HBE1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002850
tested applications
WB
Description
HBE1 Antibody is a Rabbit Polyclonal antibody against HBE1. The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Hemoglobin Subunit Epsilon (HBE1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P02100 |
Gene ID | 3046 |
NCBI Accession | NP_005321.1 |
Background | Antibody anti-HBE1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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HBE1 antibody
The hemoglobin molecule is a tetramer consisting of two alpha-and two beta-globin-like chains. HBE1(hemoglobin epsilon chain) is a beta-type chain of hemoglobin predominantly expressed during the embryonic stage(21321359). The HBE1 has been regarded as the best marker for fetal nucleated red blood cells(NRBCs) . This antibody can be used to label and isolate fetal cells from maternal blood and may be useful in prenatal diagnosis(15906407).
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