Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)
429€ (100 tests)
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935106861
info@markelab.com
name
Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx139249
tested applications
IF/ICC, FCM
Description
CD34 Antibody is a Mouse Monoclonal against CD34.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 20 µl/100 µl of whole blood or 106 cells. Validated in IHC-P and ICC. Optimal dilutions/concentrations should be determined by the end user. The content of a vial (2 ml) is sufficient for 100 tests. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 |
| Clone ID | E334 |
| Size 1 | 100 tests |
| Tested Applications | IF/ICC, FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P28906 |
| Gene ID | 947 |
| Alias | Hematopoietic progenitor cell antigen CD34 |
| Background | Antibody anti-CD34 |
| Status | RUO |
Descripción
CD34 is a well-known cell surface glycoprotein that is primarily expressed on hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells, and is used as a marker to identify early stem cells within the bone marrow and other tissues. This molecule has become an invaluable tool in both research and clinical medicine, particularly in the isolation and characterization of hematopoietic stem cells for bone marrow transplantation, and in the study of angiogenesis due to its presence on vascular endothelium. The CD34 protein belongs to the family of sialomucin-like adhesion molecules. Initially, it was identified as a marker on hematopoietic progenitor cells and subsequently found to be involved in various physiological processes, such as cell adhesion, cell signaling, and migration. CD34 is a highly glycosylated protein, and its extensive post-translational modifications, including sialylation and O-glycosylation, play important roles in its function, particularly in regulating cell-cell interactions and hematopoietic cell homing.
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