Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (FITC)
169€ (20 µg)
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935106861
info@markelab.com
name
Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx313243
Description
CD34 Antibody (FITC) is a Rabbit Polyclonal against CD34 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28906 |
| Gene ID | 947 |
| NCBI Accession | NP_001020280.1, NM_001025109.1 |
| OMIM | 142230 |
| Alias | Hematopoietic progenitor cell antigen CD34 |
| Background | Antibody anti-CD34 |
| Status | RUO |
Descripción
CD34 is a well-known cell surface glycoprotein that is primarily expressed on hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells, and is used as a marker to identify early stem cells within the bone marrow and other tissues. This molecule has become an invaluable tool in both research and clinical medicine, particularly in the isolation and characterization of hematopoietic stem cells for bone marrow transplantation, and in the study of angiogenesis due to its presence on vascular endothelium. The CD34 protein belongs to the family of sialomucin-like adhesion molecules. Initially, it was identified as a marker on hematopoietic progenitor cells and subsequently found to be involved in various physiological processes, such as cell adhesion, cell signaling, and migration. CD34 is a highly glycosylated protein, and its extensive post-translational modifications, including sialylation and O-glycosylation, play important roles in its function, particularly in regulating cell-cell interactions and hematopoietic cell homing.
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