Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (FITC)

Este producto es parte de CD34 - CD34 molecule
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364€ (100 tests)

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935106861
info@markelab.com
name
Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx139248
tested applications
FCM

Description

CD34 Antibody is a Mouse Monoclonal against CD34.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Hematopoietic Progenitor Cell Antigen CD34 (CD34)
Host
Mouse
Reactivity
Human, Monkey
Recommended Dilution
FCM: 20 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (2 ml) is sufficient for 100 tests.
Clonality
Monoclonal
Conjugation
FITC
Isotype
IgG1
Clone ID
R656
Size 1
100 tests
Tested Applications
FCM
Buffer
Stabilizing PBS solution containing 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
P28906
Gene ID
947
Alias
Hematopoietic progenitor cell antigen CD34
Background
Antibody anti-CD34
Status
RUO

Descripción

CD34 is a well-known cell surface glycoprotein that is primarily expressed on hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells, and is used as a marker to identify early stem cells within the bone marrow and other tissues. This molecule has become an invaluable tool in both research and clinical medicine, particularly in the isolation and characterization of hematopoietic stem cells for bone marrow transplantation, and in the study of angiogenesis due to its presence on vascular endothelium. The CD34 protein belongs to the family of sialomucin-like adhesion molecules. Initially, it was identified as a marker on hematopoietic progenitor cells and subsequently found to be involved in various physiological processes, such as cell adhesion, cell signaling, and migration. CD34 is a highly glycosylated protein, and its extensive post-translational modifications, including sialylation and O-glycosylation, play important roles in its function, particularly in regulating cell-cell interactions and hematopoietic cell homing.

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