Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (APC)
637€ (100 tests)
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935106861
info@markelab.com
name
Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx270569
tested applications
FCM
Description
Cluster Of Differentiation 34 (CD34) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against Cluster Of Differentiation 34 (CD34) for use in flow cytometry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | APC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. |
| Dry Ice | No |
| Alias | Hematopoietic progenitor cell antigen CD34 |
| Background | Antibody anti-CD34 |
| Status | RUO |
Descripción
CD34 is a well-known cell surface glycoprotein that is primarily expressed on hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells, and is used as a marker to identify early stem cells within the bone marrow and other tissues. This molecule has become an invaluable tool in both research and clinical medicine, particularly in the isolation and characterization of hematopoietic stem cells for bone marrow transplantation, and in the study of angiogenesis due to its presence on vascular endothelium. The CD34 protein belongs to the family of sialomucin-like adhesion molecules. Initially, it was identified as a marker on hematopoietic progenitor cells and subsequently found to be involved in various physiological processes, such as cell adhesion, cell signaling, and migration. CD34 is a highly glycosylated protein, and its extensive post-translational modifications, including sialylation and O-glycosylation, play important roles in its function, particularly in regulating cell-cell interactions and hematopoietic cell homing.
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