Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

Este producto es parte de CD34 - CD34 molecule
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208€ (20 µl)

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935106861
info@markelab.com
name
Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx006947
tested applications
ELISA, WB, IF/ICC

Description

CD34 Antibody is a Rabbit Polyclonal Antibody against CD34.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Hematopoietic Progenitor Cell Antigen CD34 (CD34)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P28906
Gene ID
947
NCBI Accession
NP_001020280
Alias
Hematopoietic progenitor cell antigen CD34
Background
Antibody anti-CD34
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

CD34 is a well-known cell surface glycoprotein that is primarily expressed on hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells, and is used as a marker to identify early stem cells within the bone marrow and other tissues. This molecule has become an invaluable tool in both research and clinical medicine, particularly in the isolation and characterization of hematopoietic stem cells for bone marrow transplantation, and in the study of angiogenesis due to its presence on vascular endothelium. The CD34 protein belongs to the family of sialomucin-like adhesion molecules. Initially, it was identified as a marker on hematopoietic progenitor cells and subsequently found to be involved in various physiological processes, such as cell adhesion, cell signaling, and migration. CD34 is a highly glycosylated protein, and its extensive post-translational modifications, including sialylation and O-glycosylation, play important roles in its function, particularly in regulating cell-cell interactions and hematopoietic cell homing.

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