Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

Product specifications

Primary Antibodies

Hematopoietic Progenitor Cell Antigen CD34 (CD34)

Rabbit

Human

ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified by antigen affinity column chromatography.

100 µg

1 mg

Lyophilized

ELISA, WB

Prior to lyophilization: 1% BSA and 0.02% NaN3.

Shipped within 7-15 working days.

Store at -20 °C. Avoid repeated freeze/thaw cycles.

No

BC039146

Hematopoietic progenitor cell antigen CD34

Antibody anti-CD34

RUO

Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

CD34 is a well-known cell surface glycoprotein that is primarily expressed on hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells, and is used as a marker to identify early stem cells within the bone marrow and other tissues. This molecule has become an invaluable tool in both research and clinical medicine, particularly in the isolation and characterization of hematopoietic stem cells for bone marrow transplantation, and in the study of angiogenesis due to its presence on vascular endothelium. The CD34 protein belongs to the family of sialomucin-like adhesion molecules. Initially, it was identified as a marker on hematopoietic progenitor cells and subsequently found to be involved in various physiological processes, such as cell adhesion, cell signaling, and migration. CD34 is a highly glycosylated protein, and its extensive post-translational modifications, including sialylation and O-glycosylation, play important roles in its function, particularly in regulating cell-cell interactions and hematopoietic cell homing.

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