Heat Shock Protein 70 (HSP70) Antibody (APC)
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Description
HSP70 Antibody is a Mouse Monoclonal against HSP70.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Heat Shock Protein 70 (HSP70) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Cow, Worm, Dog, Chicken, Drosophila, Fish, Guinea pig, Hamster, Monkey, Pig, Rabbit, Sheep |
| Recommended Dilution | WB: 1/1000, IHC: 1/10000, IF/ICC: 1/1000, FACS: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG1 |
| Purification | Purified by Protein G. |
| Size 1 | 200 µg |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM, FACS, IEM, BL, AM |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.1% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P0DMV8, P0DMV9 |
| Gene ID | 3303 |
| NCBI Accession | NP_005336.3 |
| Background | Antibody anti-HSP70 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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anti- HSP70 antibody
HSPA1A, collectively known as HSP70(also referred to HSP72), is a stress-inducible member of heat-shock protein 70(HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines.
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