Hamster Interferon Gamma (IFNG) ELISA Kit

Este producto es parte de IFNG - interferon gamma
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773.5€ (96 tests)

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935106861
info@markelab.com
name
Hamster Interferon Gamma (IFNG) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx257601
tested applications
ELISA

Description

Hamster IFNg ELISA Kit is an ELISA Kit against IFNg.

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Interferon Gamma (IFNG)
Reactivity
Hamster
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
15.6 pg/ml - 1000 pg/ml
Sensitivity
< 9.38 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
O35497
Alias
IFG,IFI,IMD69,IFN-gamma,Immune interferon
Background
Elisa kits for IFNG
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Interferon Gamma (IFNG) is a pivotal cytokine of the immune system, classified as a type II interferon, and is primarily produced by activated T lymphocytes, natural killer (NK) cells, and NKT cells. Unlike type I interferons, IFNG signals through a distinct receptor, the interferon gamma receptor (IFNGR), leading to the activation of the JAK-STAT pathway and the induction of a unique set of genes critical for immune defense. IFNG plays a central role in coordinating both innate and adaptive immune responses, including macrophage activation for enhanced phagocytosis and antigen processing, upregulation of MHC class I and II molecules to improve antigen presentation, and stimulation of cytotoxic T cells. It is also essential in granuloma formation to contain intracellular pathogens, such as Mycobacterium tuberculosis. Dysregulation of IFNG activity is implicated in various inflammatory and autoimmune conditions, as well as chronic infections. Its therapeutic potential in immunotherapy and as a biomarker in certain cancers and infectious diseases remains an active focus of study.

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